Dr. Sreejith Raveendran Profile

Dr. Sreejith Raveendran

Ph.D.,
Post Doctoral Researcher
Bio Nano Electronics Research Center,
Toyo University, Kawagoe, Saitama, 350-8585, Japan.
Ph :( +81)-(0)492-39-1636/1375/1640(Off)
Mob: (+81)-(0)-80-320-99159
Email: sreejithr84@gmail.com
http://www.drsakthikumar.com/sreejith.php

Academic Profile:

Doctor of Life Sciences, Bionano Science (2010 ~2013)
Master of Science- Microbiology- (2005 ~2007)
Post graduate diploma in Bioinformatics- (2005 ~2006)
Bachelor of Science-Microbiology- (2002 ~2005)

Achievements & Awards:

Best poster prize award for Nanosmat 2014, International conference on surface, coatings and nanostructured materials, Trinity college, Dublin, Ireland.
Student grant award for International Conference on Nanoscience + Technology (ICNT) 2012, held at Paris, France, on 23rd -27th July 2012.
Monbukagakuksho fellowship, MEXT, Japan - 2010 for Doctoral studies in Bionanotechnology.
University First rank in MSc. Microbiology – 2005-07 Batches under Bharathidasan University, Tiruchirapally, Tamil Nadu, India.
Gold Medal for achieving University First Rank in MSc. Microbiology by J.J.College of Arts & Science, Pudukkotai, Tamil Nadu, India.

Research Interests

Gold nanocage based combinatorial therapeutic approaches for cancer therapy and diagnosis.
Novel aspects of nanodrug delivery and extremophilic microbiology.
Immunological stimulations, microbiology, molecular & cellular mechanisms behind infectious diseases.
Cancer metastasis, tumor biology, medical immunology and In vivo molecular toxicological studies.
Introduction & application of novel biocompatible polysaccharides of bacterial origin in nanomedicine and biotechnology.

Publications:

Targeting self-renewal pathways in cancer stem cells: Clinical implications for cancer therapy.
Ankita Borah, Sreejith Raveendran, Ankit Rochani, Toru Maekawa, D. Sakthi Kumar.
Oncogenesis, 2015, 4, e177; doi:10.1038/oncsis.2015.35 .
Extremophilic polysaccharide nanoparticles for cancer nanotherapy and evaluation of antioxidant properties.
Sreejith Raveendran, Vivekanandan Palaninathan, Yutaka Nagaoka, Takahiro Fukuda, Seiki Iwai, Toshiaki Higashi, Toru Mizuki, Yasushi Sakamoto, P. V. Mohanan, Toru Maekawa, D. Sakthi Kumar.
International Journal of Biological Macromolecules, 2015, 76, 310- 319.
N2 Plasma assisted one- step alignment and patterning of graphene oxide on SiO2 /Si substrate via Langmuir Blodgett technique.
Neha Chauhan, Vivekanandan Palaninathan, Sreejith Raveedran, Aby C. Poulose, Yoshikata Nakajima, Takashi Hasumura, Takashi Uchida, Tatsuro Hanajiri, Toru Maekawa, D. Sakthi Kumar.
Advanced Materials Interfaces, 2015, 2, 1400515.
Keratin degradation by bacteria and fungi isolated from poultry farm and plumage.
Sivakumar Nallusamy and Sreejith Raveendran.
British Poultry Science. DOI: 10.1080/00071668.2014.996119
Acetosulfation of bacterial cellulose: An unexplored promising incipient candidate for highly transparent thin film.
Vivekanandan Palaninathan, Neha Chauhan, Aby Cheruvathoor Poulose, Sreejith Raveendran, Toru Mizuki, Takashi Hasumura, Takahiro Fukuda, Hisao Morimoto,Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar.
Material Express, 2014, 4(5), 415-421.
Extremophilic polysaccharide for bioreduction and passivation of gold nanoparticles and photothermal ablation of cancer cells.
Sreejith Raveendran, Neha Chauhan, Vivekanandan Palaninathan, Yutaka Nagaoka, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar.
Particle & Particle System Characterization, 2015, 32, 54-64.
Bacterial exopolysaccharide based magnetic nanoparticles: A versatile nanotool for cancer cell imaging, targeted drug delivery and synergistic effect of drug and hyperthermia mediated cancer therapy.
Sivakumar Balasubramanian, Aswathy Ravindran Girija, Sreejith Raveendran, Yutaka Nagaoka, Seki Iwai, Masashi Suzuki, Takahiro Fukuda, Takshi Hasumura, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar.
Journal of Biomedical Nanotechnology , 2014, 10, 885-899.
Evaluation of toxicity of maura reduced graphene oxide using in vitro systems.
Reshma. S. Cherian#, Sreejith Raveendran#, Syama. S, Sruthi. S, Gayathri. V, Toru Maekawa, D. Sakthi Kumar, Mohanan PV. (# Authors equally contributed)
Journal of Nanomedicine & Nanotechnology , 2014, 5:3.
Green approach for augmenting biocompatibility of quantum dots by extremophilic polysaccharide conjugation and nontoxic bioimaging.
Sreejith Raveendran, Aswathy Ravindran Girija, Sivakumar Balasubramanian, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar.
ACS Sustainable Chemistry & Engineering, 2014, 2 (7), 1551- 1558.
In vitro evaluation of antioxidant defense mechanism and hemocompatibility of mauran.
Sreejith Raveendran, Vivekanandan Palaninathan, Neha Chauhan, Yasushi Sakamoto, Yasuhiko Yoshida, Toru Maekawa, P. V. Mohanan, D. Sakthi Kumar.
Carbohydrate Polymers, 2013, 98; 108- 115.
Pharmaceutically versatile sulfated polysaccharide based bionano platforms.
Sreejith Raveendran, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar.
Nanomedicine: Nanotechnology, Biology and Medicine, 2013, 9; 605-626.
Ecofriendly route for synthesis of highly conductive graphene using extremophiles for green electronics and bioscience.
Sreejith Raveendran, Neha Chauhan, Yoshikata Nakajima, Higashi Toshiaki, Shunji Kurosu, Yuji Tanizawa, Ryugo Tero, Yasuhiko Yoshida, Tatsuro Hanajiri, Toru Maekawa, Pulickel. M. Ajayan, Adarsh Sandhu, D. Sakthi Kumar.
Particle & Particle System Characterization, 2013, 30; 573- 578.
Biocompatible nanofibers based on extremophilic bacterial polysaccharides from Halomonas maura.
Sreejith Raveendran, Brahatheeswaran Dhandayuthapani, Yutaka Nagaoka, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar.
Carbohydrate Polymers, 2013, 92; 1225-1233.
Bacterial polysaccharide based nanoparticles for sustained drug delivery, cancer chemotherapy and bioimaging.
Sreejith Raveendran, Aby. C. Poulose, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar.
Carbohydrate Polymers, 2013, 91; 22- 32.
Multifunctional biocompatible fluorescent carboxymethyl cellulose nanoparticles.
Aswathy Ravindran Girija, Sivakumar Balasubramanian, Brahatheeswaran Dhandayuthapani, Sreejith Raveendran, Tomufomi Ukai, Takahiro Fukuda, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar.
Journal of Biomaterials and Nanobiotechnology. 2012, 3; 254- 261.
PEG Coated Biocompatible Cadmium Chalcogenide Quantum Dots for Targeted Imaging of Cancer Cells.
Aby. C. Poulose, Srivani Veeranarayanan, Sheikh Mohammed, Sreejith Raveendran, Yutaka Nagaoka, Yasuhiko Yoshida, Toru Maekawa, D. Sakthi Kumar.
Journal of Fluorescence, 2012, 22 (3); 931- 944.
A bionano outlook of natural & synthetic polymers in therapeutics and material science.
Sreejith Raveendran#, Athulya Aravind#, Toru Maekawa, D. Sakthi Kumar. (# Authors equally contributed). (Under Communication).
Ex- vivo and in vitro evaluation of antioxidant property, hemocompatibility and cytotoxicity of bacterial cellulose sulfate.
Vivekanandan Palaninathan, Sreejith Raveendran, Neha Chauhan, Toru Mizuki, Takashi Uchida, Yoshikata Nakajima, Tomofumi Ukai, Yasushi Sakamoto, P. V. Mohanan, Toru Maekawa, D. Sakthi Kumar. (Under Communication).

Conferences:

“Biopassivated theragnostic nanocages for combinatorial therapy of cancer”- invited lecture at The City College of the City University of New York, Soft Materials Research Laboratory, Center for Discovery and Innovation & Department of Chemistry, New York City, USA on 4th Dec 2015 [INVITED TALK].
“Engineering Au-Ag based therapgnostic nanocages for combinatorial therapy of breast cancer” for MRS, Fall meeting & Exhibit 2015, Hynes convention center, Boston, Massachusetts, USA, on 28th Nov- 4th Dec 2015 [ORAL].
“Cancer therapy based on shape dependent biocompatible gold nanostructures”, 9th International conference on surfaces, coatings and nanostructured materials, Trinity college, Dublin, Ireland, on 8th-11th Sept.2014 [ORAL].
“Extremophilic microbiology & cancer therapy in nanomedicine”- Invited lecture at the University of Brighton, The School of Pharmaceutical Sciences, Brighton, United Kingdom, on 3rd-4th Sept. 2014. [INVITED TALK].
“Pharmaceutically versatile mauran for biomedical & material science applications” for 11th International symposium on Bioscience and Nanotechnology held at Toyo University, Tokyo, Japan on 15th Nov 2013 [POSTER].
“Prospects of extremophilic microbiology & sulfated polysaccharides in cancer therapy & nanomedicine” for Second Sustainable Nanotechnology Organization Conference 2013, at Santa Barbara, California, USA, on 3rd- 5th Nov 2013 [ORAL].
“Bioreduction and stabilization of gold nanoparticles using extremophilic exopolysaccharide, mauran & photothermal ablation of cancer cells” for 10th International symposium on Bionanoscience held at Toyo University, Tokyo, Japan on 7th & 8th Dec 2012 [POSTER].
“Extremophilic bacterial polysaccharide based nanoparticles for sustained drug delivery, cancer chemotherapy and cellular imaging” for International Conference on Nanoscience + Technology (ICNT) 2012, held at Paris, France, on 23rd -27th July 2012 [ORAL].
“Ecofriendly Reduction of Graphene Oxide Using Extremophile Bacteria” for Graphene 2012 International Conference held at Brussels, Belgium on 10th- 13th of April 2012 [POSTER].
“Extremophiles for biologically- based reduction of graphene oxide into graphene” for 2012 Materials Research Society (MRS) Spring meeting & Exhibit at San Francisco, California, USA on 9th- 13th of April 2012 [POSTER].
“Extremophiles in the biological reduction of graphene oxide” for 9th International symposium on Bioscience and Nanotechnology held at Toyo University, Tokyo, Japan on 10th Dec 2011 [POSTER].
“Computer Simulation of Drug Release Kinetics of Mauran-Chitosan Nanoparticles using COMSOL Multiphysics” for the COMSOL Conference 2011, organized by Keisoku Engineering System Co., Ltd., held at Tokyo, Japan on 2nd Dec 2011 [INVITED TALK & POSTER].
“Introduction of Extremophilic Exopolysaccharides in Bio- Nanotechnology” for The Asia- Pacific Interdisciplinary Research Conference 2011, organized by Electronics- Inspired Interdisciplinary Research Institute (EIIRIS) held at Toyohashi University of Technology, Aichi, Japan on 17th Nov 2011 [POSTER].
“Anticancer Studies of Mauran and its Applications in Nanotechnology” for 2nd India-Japan symposium organized by Indian Scientists’ Association of Japan based on health and environment held at the Indian Embassy, Tokyo, Japan on 7th Oct 2011 [POSTER].
“Formulation of extremophilic bacterial sulfated polysaccharide based nanoparticles” for 8th International symposium on Bioscience and Nanotechnology held at Toyo University, Tokyo, Japan on 17th -18th Dec 2010 [POSTER].

Professional Appointments:

Post Doctoral Researcher at Bio- Nano Electronics Research Center, Toyo University, Kawagoe campus, Saitama, Japan (From April 2013 to till date). Performing research in Bionanotechnology, cancer biology and microbiology. Dealing with the In vitro and In vivo toxicity analysis and development of candidate nano formulations against various cancer tissues. Also, dealing with tissue culture and engineering using stem cells for nanofibers developed using biological polymers.
Research Associate- Microbiology in Infection Pharmacology department of AstraZeneca India Pvt.Ltd, Bangalore, India (From Sep 2009 to Mar 2010). High through put screening of candidate drugs from libraries as a part of drug discovery program for tuberculosis. Biosafety level (BSL-3) trained, Analysis of mutants by PCR amplification and sequence analysis.
Junior Research Associate in ABL Biotechnologies Ltd, Chennai, India (From Feb 2008 to Aug 2009). Maintaining a wide library of algal cultures, extraction of commercially important biomolecules and pigments from algae and fungal species via controlled fermentation processes, drafting project proposals for DBT, DST and CSIR (Government of India).
Trainee Microbiologist in the Quality Control-Microbiology department of SAJ Flight Services Pvt. Ltd, Cochin International Airport, Cochin, India. Food quality control based on HACCP and ISO standards.

Research works:

Gold nanocage based combinatorial therapeutic approaches for cancer therapy and diagnosis.
Extremophilic bacterial sulfated polysaccharide based nanoparticles for sustained drug delivery, cancer chemotherapy and bio- imaging.
Estimation of biological properties like antioxidant, anti-angiogenic and anticancer activities of mauran and polysaccharide extracted from Halomonas eurihalina.
Fabrication of biocompatible nanofibers scaffolds using extremophilic bacterial exopolysaccharides for tissue engineering applications.
Proliferation, migration and differentiation of mouse fibroblast cells within polysaccharide nanofibers scaffolds and biocompatibility assay for nanofibers using stem cells, KUSA.
Synthesis of mauran stabilized gold nanoparticle structures for various biological applications.
Stabilization of quantum dots using bacterial polysaccharides for biocompatible live imaging of mammalian cell lines.
High through put bioimaging and anticancer efficacy studies using bacterial exopolysaccharide based nanoparticles.
Ecofriendly reduction of graphene oxide to produce highly conductive graphene using extremophilic bacteria for green electronics.
Computer Simulation of Drug Release Kinetics of Mauran-Chitosan Nanoparticles using COMSOL Multiphysics.
High throughput screening and toxicity assays for various candidate drugs in the program of drug discovery for tuberculosis in H37Rv strain of Mycobacterium tuberculosis & M. smegmatis.
Extraction, estimation and analysis of pharmacologically active ingredients from marine microbes especially from algae.
Sustained drug delivery using liposomes and microspheres”.
Extraction of C-phycocyanin and its action on COX-2 inhibition.
“A study on keratinolytic microorganisms isolated from poultry feathers” at Suguna Poultry Farm Ltd. Coimbatore, India.
“Antimicrobial activity of seed extract of Terminalia chebula” at Indian Institute of Chemical Technology (Council of Scientific and Industrial Research), Hyderabad, India.