Dr. D. BRAHATHEESWARAN (Thesis Title: Advanced hybrid electrospun nanofibrous scaffolds for biomedical applications) Research Fellow Department of Chemistry, National University of Singapore Singapore

Educational Qualifications:

• Ph.D., Bio - Nanotechnology, Toyo University, Kawagoe, Japan.
• M. Sc., Biotechnology, Bharathidasan University, Trichy, India.
• B. Sc., Chemistry, Bharathidasan University, Trichy, India.

Professional History:

1. Research Fellow, Department of Chemistry, National University of Singapore, Singapore. (From April 2012)
2. Research Assistant, Bio Nano Electronics Research Center, Toyo University, Japan. (April 2009 - March 2012)
3. Junior Research Fellow, Centre for Nanotechnology & Advanced Biomaterials, SASTRA University, Thanjavur. (September 2006 - March 2009)
4. Research Assistant, Centre for Advanced Research in Indian System of Medicine, SASTRA University, Thanjavur. (July 2005 - November 2006)
5. Project Assistant, School of Chemical & Biotechnology, SASTRA University, Thanjavur. (June 2004 - June 2005).

Awards, Fellowships and Honors:

1. Post doctoral fellowship by the National University of Singapore - April 2012
2. Received Monbukagauksho fellowship, MEXT, Japan - 2009 - 2012
3. Received Korean Govt. fellowship, 2008
4. II nd Rank Holder in university in M.Sc., Biotechnology.
5. Junior Research Fellow, DST, Government of India, India
6. Internship fellowship (Dec '03 to March '04), National University of Singapore.

Current Research Area:

List of Publications

Journal

1. Biomimetic smart nanocomposite: Quantum dot encapsulated zein electrospun fluorescent nanofiber. Brahatheeswaran D, Aby C P, Y Nagaoka, T Hasumura, Y Yoshida, T Maekawa, D S Kumar.
   Biofabrication, 2012; 7, 045001, DOI:10.1088/1758 - 5082/4/2/025008.
2. Hybrid fluorescent curcumin loaded zein electrospun nanofibrous scaffold for biomedical applications. Brahatheeswaran D, Anila M, Aswathy RG, Y Nagaoka, Venugopal K, Y Yoshida, T Maekawa, D S Kumar.
   Biomedical Materials, 2012; 4, 025008, DOI:10.1088/1748 - 6041/7/4/045001
3. Evaluation of antithrombogenicity and hydrophilicity on Zein - SWCNT electrospun fibrous nanocomposite scaffolds. Brahatheeswaran D, Saino HV, Aswathy RG, Y Yoshida, T Maekawa, D S Kumar.
   International Journal of Biomaterials, 2012; DOI:10.1155/2012/345029 .
4. Polymeric Scaffolds in Tissue Engineering Application : A Review. Brahatheeswaran D, Y Yoshida, T Maekawa, D S Kumar.
   International Journal of Polymer Science. 2011; DOI:10.1155/2011/290602, 19 pages.
5. Fabrication and characterization of nanofibrous scaffold developed by electrospinning. Brahatheeswaran D, Y Yoshida, T Maekawa, D S Kumar.
   Materials Research. 2011; 14(3): 317 - 325. DOI: 10.1590/S1516 - 14392011005000064
6. Biocompatible fluorescent zein nanoparticles for simultaneous bioimaging and drug delivery application. Aswathy RG, Sivakumar B, Brahatheeswaran D, T Fukuda, Y Yoshida, T Maekawa, D S Kumar.
   Advances in Natural Sciences:Nano Science and Nanotechnology. 2012; 3, 025006 DOI:10.1088/2043 - 6262/3/2/025006
7. Multifunctional biocompatible fluorescent carboxymethyl cellulose nanoparticles. Aswathy RG, Sivakumar B, Brahatheeswaran D, Sreejith R, T Ukai , T Fukuda, Y Yoshida, T Maekawa, Kumar DS.
   Journal of Biomaterials and Nanobiotechnology, 2012; 3, 254, DOI:10.4236/jbnb/2012.322031.
8. Green synthesis, characterization and in vitro biocompatibility of starch capped PbSe nanoparticles. Aswathy RG, Sivakumar B, Brahatheeswaran D, Y Yoshida, T Maekawa, D S Kumar.
   Advanced Science Letters, 2012 (press).
9. Biocompatible fluorescent jelly quantum dots for bioimaging. Aswathy RG, Sivakumar B, Brahatheeswaran D, T Ukai, Y Yoshida, T Maekawa, D S Kumar.
   Materials Express, 2011; DOI:10.1166/mex.2011.1045.
10. Amyloid - binding aptamer conjugated curcumin - PLGA nanoparticle for potential use in Alzheimer's Disease. Anila M, Athulya A, Brahatheeswaran D, T Fukuda, Y Nagaoka, T Hasumura, S Iwai, H Morimoto, Y Yoshida, T Maekawa, K Venugopal, D S Kumar. Bio Nano Science. 2011; DOI 10.1007/s12668 - 012 - 0040 - y.
11. Fabrication and characterization of chitosan - gelatin blend nanofibers for skin tissue engineering. Brahatheeswaran D, Uma Maheswari K, Swaminathan S.
    Journal of Biomedical Materials Research B: Applied Biomaterials. 2010; 94(1):264 - 272.
12. Anti - hyperglycemic activities of aqueous and ethanolic extract of Cynodon dactylon (Linn) in streptozotocin induced diabetic rats. Mahesh N, Brahatheeswaran D.
    Asian Journal of Biochemistry. 2007;2(1):66 - 72.
13. Prevalence of ESBL producing strains in tuberculosis patients. Jayapradha R, Murugesh S, Mahesh N, Brahatheeswaran D.
    Research Journal of Microbiology. 2007;2:491 - 495.
14. Anti - inflammatory activity of Tylophora indica in albino rats. Raj CD, Shabi MM, Brahatheeswaran D, Mahesh N.
    Journal of Pharmacology and Toxicology. 2006;1:490 - 492.

Conferences:

1. Electrospun fluorescent nanofibrous scaffold for drug delivery application. Brahatheeswaran D, Mathew A, Aswathy RG, Nagaoka Y, Yoshida Y, Maekawa T, Kumar DS. 9th International Seminar on Bioscience and Nanotechnology, December 10, 2011, Toyo University, Tokyo, Japan.
2. Biocompatible fluorescent zein nanoparticles. Aswathy RG, Sivakumar B, Brahatheeswaran D, Yoshida Y, Maekawa T, Kumar DS. 9th International Seminar on Bioscience and Nanotechnology, December 10, 2011, Toyo University, Tokyo, Japan.
3. Material designed for medical applications: zein - swcnt nanocomposite scaffold (Poster). Brahatheeswaran D, Saino HV, Yoshida Y, Maekawa T, Kumar DS. India - Japan symposium on global challenges in health and environment, October 7, 2011, Tokyo, Japan. [4] Curcumin nanoparticle for targeting alzheimer's disease - A way of herbal renaissance (Oral/Poster). Mathew A, Brahatheeswaran D, Fukuda T, Nagaoka Y, Yoshida Y, Maekawa T, Kumar DS. India - Japan symposium on global challenges in health and environment, October 7, 2011, Tokyo, Japan.
4. Folate conjugated biocompatible fluorescent carboxymethyl cellulose nanoparticle. (Poster). Aswathy RG, Sivakumar B, Brahatheeswaran D, Yoshida Y, Maekawa T, Kumar DS. India - Japan symposium on global challenges in health and environment, October 7, 2011, Tokyo, Japan.
5. Biomimetic nanofibrous scaffolds: Preparation and characterization of silk fibroin / Zein blend nanofibers (Oral/Poster). Brahatheeswaran D, Yoshida Y, Maekawa T, Kumar DS. NanoBioTech - Montreux, November 15 - 17, 2010, Switzerland.
6. In vitro hemocompatibility studies of Zein containing Silk fibroin nanofiber Scaffold (Poster). Brahatheeswaran D, Yoshida Y, Maekawa T, Kumar DS. 8th International Seminar on Bioscience and Nanotechnology, December 17 - 18, 2010, Toyo University, Tokyo, Japan
7. Electrospinning technology for nanofibrous scaffolds in Tissue Engineering (Poster). Brahatheeswaran D, Yoshida Y, Maekawa T, Kumar DS. 7th International Seminar on Bionano Science, November 20 - 21, 2009, Toyo University, Tokyo, Japan.
8. Polymeric nanofibrous scaffolds and its application for tissue engineering. Brahatheeswaran D, A review department presentation, Jun, 2009, Toyo University, Kawagoe, Japan.
9. Fabrication and characterization of Chitosan - Gelatin blend nanofiber. Brahatheeswaran D, Uma Maheswari K, Swaminathan S. Ist International conference on Nanobio (Tissue engineering and stem cell research using nanomaterials) Feb, 2009, Amrita centre of Nanoscience, Kochi, India.
10. Development of Chitosan nanofiber. Brahatheeswaran D, Uma Maheswari K, Swaminathan S. 2nd Bangalore Nano Conference, Dec, 2008, Bangalore, India.
11. Targeting of thermoresposive stealth immunoliposomes to tumors with Magnetic Resonance Imaging. Brahatheeswaran D, Anuradha S, Shankar P Shyam, International Conference on Nanomedicine & Its Applications, Oct, 2007, SASTRA University, Tamilnadu, India.
12. Bacillus thuringiensis and Nuclear polyhedrosis virus as safety bioweapon against Spodoptera litura. Suganithi EMS, Mahesh N, Brahatheeswaran D. Seminar on emerging trends in life Sciences, Aug, 2006, Bishop Heber College, Tamilnadu, India.
13. Studies on Decolourization of Textile dye by Aspergillus sp. Balakrishnaraja R, Brahatheeswaran D, Mahesh N, Baburaja A. Seminar on emerging trends in life Sciences, Aug, 2006, Bishop Heber College, Tamilnadu, India.
14. Investigation and production of partially purified Plantaricin (LANTIBIOTICS) from Lactobacillus plantarum. Bhargavi R, Sheela BR, Mahesh N, Brahatheeswaran D. Seminar on emerging trends in life Sciences, Aug, 2006, Bishop Heber College, Tamilnadu, India.
15. A review of proteomics: A major new technology for the drug discovery process and target validation. Hariram B, Ramya R, Brahatheeswaran D. Mahesh N. National Level Symposium, Zeiosis'06, Nov, 2006, MET'S school of Engineering, Kerala, India.
16. An overview of Recombinant technology in today's medicine. Karthik. S, Deepak, Brahatheeswaran D, Mahesh N. National Level Symposium, Zeiosis'06. Nov, 2006, MET'S school of Engineering, Kerala, India.